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视网膜色素上皮(RPE)是维持视细胞正常代谢和功能的组织,RPE 细胞移植成功给原发于RPE 疾病的患者带来了希望。RPE细胞移植的动物实验方法有几种,作者采用JE·Turner 等从巩膜切开进行RPE 细胞移植的方法(本文简称为外路法)进行实验。发现,在正常眼压采用外路法进行RPE 细胞移植成功率低,术中前房穿刺减低眼内压能使成功率显著提高,弥补了其不足。
Retinal pigment epithelium (RPE) is to maintain the normal metabolism and function of visual cells, RPE cell transplantation success in patients with primary disease in RPE hope. There are several animal experimental methods for RPE cell transplantation. The authors used the method of JE Turner et al. To perform scleral dissection for RPE cell transplantation (referred to as the “outer route” for short). Found that the use of external pressure method in the normal intraocular pressure for transplantation of RPE low success rate, intraoperative anterior chamber puncture to reduce intraocular pressure can significantly improve the success rate, to make up for its shortcomings.