文献报导单发性骨神经纤维瘤颇为罕见。我院曾收治一例,现报告如下。病例:女,23岁,住院号59386,工人。于四年前开始,无明显原因发现右足第二趾端肿痛逐渐加重,步行困难,疼痛在夜间尤甚,影响睡眠,曾经各种治疗未有改善。局部检查:患趾端温度较低,有压痛,稍肿胀,浅表静脉怒张,发病后患趾未发生过溃烂。既往一向健康。家族史:父母兄弟姐妹均健在,无特殊疾病史。实验室检查:红细胞400万,血红蛋白11克％,白细胞6400,无机磷4.12毫克％,硷性磷酸酶(卜登斯基氏)3.4单位。 X线检查:右足第二趾末节趾骨消失,局部软组织轻度肿胀。(见图) 手术:右足第二趾截除术。病理报告:镜下检查皮骨萎缩,骨髓萎缩,内容 The literature reported that single neurofibroma is quite rare. Our hospital has admitted a case, the report is as follows now. Case: Female, 23 years old, hospital number 59386, worker. Four years ago, there was no obvious reason for the gradual aggravation of right toe second toe sores. Difficulty in walking, especially during the night, affected sleep, and various treatments had not been improved. Local examination: suffering from toe temperature is low, tenderness, a little swelling, superficial vein dilatation, onset of toe has not occurred before ulceration. Always healthy. Family history: parents, brothers and sisters are alive, no special history of disease. Laboratory tests: 4 million red blood cells, 11 grams of hemoglobin, white blood cells 6400, inorganic phosphorus 4.12 mg%, alkaline phosphatase (Budenski’s) 3.4 units. X-ray examination: the right toe second toe phalanx disappeared, mild local soft tissue swelling. (See photo) Surgery: Right foot second toe amputation. Pathology report: microscopic examination of skin atrophy, bone marrow atrophy, content