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目的观察康艾注射液协同化疗治疗急性白血病的临床疗效、骨髓抑制期血象白细胞的最低值及恢复时间、重症感染的发生率及患者生存质量等方面内容。方法将46例患者配对后随机分入治疗组(23例)和对照组(23例),对照组单纯采用化疗;治疗组同样化疗外予康艾注射液40 ml加入5%葡萄糖注射液或生理盐水250 ml静脉滴注,1次/d,连用15 d。待骨髓抑制期恢复(约2～3周)后行第二疗程化疗,两个疗程后评价疗效。结果本研究结果显示,治疗组完全缓解率与对照组比较,结果无显著性差异(P>0.05);治疗组白细胞最低值高于对照组,白细胞恢复时间短于对照组,结果有显著性差异(P<0.05);治疗组重症感染的发生率低于对照组(P<0.05),治疗组患者生存质量优于对照组(P<0.01),结果有显著性差异。结论康艾注射液有助于机体的恢复,有利于患者渡过化疗危险期,并提高生存质量。
Objective To observe the curative effect of Kangai injection combined with chemotherapy on acute leukemia, the lowest value and recovery time of leukocyte in bone marrow suppression, the incidence of severe infection and patient quality of life. Methods Forty-six patients were randomized into treatment group (23 cases) and control group (23 cases). The control group was treated with chemotherapy alone. In the treatment group, the same chemotherapy was given to 40 ml of Kangai injection plus 5% glucose injection or physiological Saline 250 ml intravenous infusion, 1 / d, once every 15 d. The bone marrow suppression period to be restored (about 2 to 3 weeks) after the second course of chemotherapy, evaluation of the efficacy of two courses. Results The results of this study showed that there was no significant difference in the complete remission rate between the treatment group and the control group (P> 0.05). The lowest leukocyte count in the treatment group was higher than that in the control group, and the recovery time of leukocytes was shorter than that in the control group (P <0.05). The incidence of severe infection in the treatment group was lower than that in the control group (P <0.05), and the quality of life in the treatment group was better than that in the control group (P <0.01). The results were significantly different. Conclusions Kangai injection can help the recovery of the body, which is good for the patients to cross the dangerous period of chemotherapy and improve the quality of life.