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目的:分享2017至2019年阿尼玛卿雪山极限越野挑战赛医疗保障经验。方法:2017至2019年青海省果洛州玛沁县阿尼玛卿雪山极限越野挑战赛组委会共派出150余名医务人员，连续3年策划和实施阿尼玛卿雪山极限越野挑战赛赛事的医疗保障和救援。保障分为领导指挥组、专家顾问组、现场医疗保障组、后方医疗保障组和医疗物资保障组，现场医疗保障组配备救护车、应急相应的医疗设备和药品分别在从包括起点到终点的8个医疗站点以及各站点间的选手路径上进行医疗保障。结果:3次赛事过程中未发生心搏骤停及猝死病例，共接诊患者56例（5例为合并伤），其中21例为轻度高原反应，擦伤8例，肌肉痉挛、拉伤13例，低血糖11例，腹痛3例。伤者均现场及时治疗观察，病情缓解。结论:实现国际越野跑协会（ITRA）认证的平均海拔最高越野赛的医疗保障成功，首先要制定科学、完善的医疗保障工作方案；赛前体检，特别是应用运动心肺功能检测，筛查出可能出现医疗意外的运动员；赛中重点监测跟踪可能出现问题的选手；各保障点与保障车紧密配合、衔接；做好各类人员的急救培训，做到有医疗意外能第一时间发现，第一时间急救，第一时间转运。阿尼玛卿雪山极限越野挑战赛赛事医疗保障对国际高原运动赛事的安全保障起到了良好的作用，为类似赛事保障工作提供了参考和借鉴。“,”Objective:To share the practice of medical care and rescue in the 2017-2019 Amne Machin extreme cross-country challenge.Methods:At the invitation of the Organizing Committee of Amne Machin extreme cross-country challenge of Maqin County of Qinghai Province. More than 150 medical personnel were sent to make the rescue plan and implement the medical security for three consecutive years. The support was divided into leading command group, expert consulting group, on-site medical support group, rear medical support group, and medical material support group. The on-site medical support group was equipped with the ambulance, corresponding emergency medical equipments and medicines to provide medical support at eight medical stations from the starting point to the endpoint and along the route between each station.Results:There were no cardiac arrest and sudden death cases during the three competitions. A total of 56 patients (5 cases of combined injuries) were received, including 21 cases of mild altitude reaction, 8 cases of abrasions, 13 cases of muscle spasm and strain, 11 cases of hypoglycemia, and 3 cases of abdominal pain. All the injured were treated and observed in time. Each patient achieved a complete remission.Conclusions:To achieve the success of medical security of the highest average altitude cross-country race certified by International Trail Running Association (ITRA), we must formulate a scientific and perfect medical security work plan in the first place: pre competition physical examination, especially the application of sports cardiopulmonary function test, screen out athletes who may have medical accidents; during the competition, focus on monitoring and tracking the players who may have problems; each support point is closely connected with the support vehicle; do a good job of first aid training for all kinds of personnel, so that medical accidents can be found, aided, and transferred at the first time. The medical care and rescue of Amne Machin extreme cross-country challenge have played a good role in the security of the international plateau sports events, which provides a reference for the security of similar events.