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探索和寻求对局部感染的外用防治方法,是外科研究工作中的基本课题之一。在外科感染中,以严重烧伤感染最为典型。自Fox首创应用磺胺嘧啶银治疗烧伤以来,所取得的进展,已广泛地影响着外科感染的治疗。本研究目的是探明外科感染,特别是烧伤感染中主要的致病菌对N~1-金属磺胺嘧啶类化合物和暗罗素(Zinc Polyanemine)及其衍生物的敏感度,以便为动物实验筛选较为敏感的外用抗菌药物。
To explore and seek topical prevention and treatment of local infection is one of the basic topics in the field of surgical research. In surgical infections, the most typical burn infection. The progress made since Fox pioneered the use of silver sulfadiazine for the treatment of burns has broadly affected the treatment of surgical infections. The purpose of this study was to investigate the sensitivity of the major pathogenic bacteria to N-1-metal sulfadiazine and Zinc Polyanemine and their derivatives in surgical infections, especially in burn wounds, in order to screen for animal experiments Sensitive topical antimicrobials.