由于先天性巨细胞病毒(CMV)感染经常引起感觉性听力丧失、认知障碍、大脑瘫痪和视力损害,是美国儿童中感觉性听力丧失和感染性中枢神经系统损害的主要原因。因此,在美国仍然是主要的公共卫生问题。预防先天性CMV感染疫苗的研制,已被国立科学院医学研究所列为重点课题。 CMV可通过妊娠期母体原发性感染传播给胎 As congenital cytomegalovirus (CMV) infections often cause sensory hearing loss, cognitive impairment, cerebral palsy, and visual impairment, they are the major causes of sensory hearing loss and infectious CNS damage in U.S. children. Therefore, the United States remains the major public health issue. The prevention of congenital CMV vaccine development, has been the National Academy of Sciences Institute of Medicine as a key issue. CMV can be transmitted to the fetus by gestational maternal primary infection