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对30例有并发症T_2DM病患者、20例无发症T_2DM病患者及22例健康支援者检测双侧大脑前动脉(ACA)、大脑中动脉(MCA)、大脑后动脉(PCA)和双侧椎动脉(VA)及基底动脉(BA)的平均阻力指数(RI)和搏动指数(PI)。并检测HCY、胆固醇(TC)、甘油三脂(TG)、空腹血糖(FBG)、餐后2小时血糖(PPBG)及糖化血红蛋白(HbAlc),结果显示并发症组TC、TG、FBG、PPBG、HbAlc、HCY及PI、RI明显高于无并发症组和对照组,差异具有统计学意义(P<0.05)。且并发症组和单纯T_2DM组的TC、TG、FBG、PPBG、HbAlc、HCY及PI、RI均高于对照组,并有统计学意义(P<0.05)。反映HCY水平升高与T_2DM患者的脑动脉粥样硬化密切相关。
Twenty patients with T 2 DM, 20 patients with uncomplicated T 2 DM and 22 healthy volunteers were enrolled in this study. Bilateral ACA, MCA, PCA and Bilateral Vertebral artery (VA) and basilar artery (BA) average resistance index (RI) and pulsatility index (PI). TC, TG, FBG, FBG, PPBG and HbAlc were measured. The results showed that TC, TG, FBG, PPBG, HbAlc, HCY and PI, RI were significantly higher than those without complications and control group, the difference was statistically significant (P <0.05). The levels of TC, TG, FBG, PPBG, HbAlc, HCY, PI and RI in the complication group and T 2DM group were significantly higher than those in the control group (P <0.05). Reflect the elevated levels of HCY and T2DM patients with cerebral atherosclerosis are closely related.