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Monoclonal antibodies(MoAbs)were developed against epidermal growth factor(EGF)receptor on thehuman epidermoid carcinoma cell line A431.The A431 antigen recognized by the MoAbs has an apparentmolecular weight of approximately170.000.with the same molecular weight as the CNE—2 cell line(poorlydifferentiated nasopharyngeal carcinoma).Administration of anti—EGF receptor MoAbs inhibited tumor for-
Monoclonal antibodies (MoAbs) were developed against epidermal growth factor (EGF) receptor on the human epidermoid carcinoma cell line A431.The A431 antigen was recognized by the MoAbs has an apparent molecular weight of approximately 170.000. with the same molecular weight as the CNE-2 cell line (poorly differentiated nasopharyngeal carcinoma) .Administration of anti-EGF receptor MoAbs inhibited tumor for-