Duchenne肌营养不良症及重度血友病等X·连锁性疾病的女性携带者对生育问题上的选择往往是不怀孕,或则冒1/2危险分娩一个男病孩,现今,通常可用羊膜穿刺及胎儿细胞培养来决定胎儿性别,若为男性,多数妊妇携带者终止妊娠,那样就失去50%正常胎儿的机会。作者应用血浆ⅧC及Ⅸ因子测定法产前诊断使血友病携带者孕妇能分娩正常的健康男孩。在直视胎儿镜下对22例15～22孕周病例的采集胎儿血,测定其血浆ⅧC及Ⅸ因子水平,平均值分别为50国际单位/分升(标准差12.8)及12.5国际单位/分升(标准差2.4)。22例中7例为有诊断价值的血友病可能携带者,内属专性者2例,高度假定 Duchenne muscular dystrophy and severe hemophilia X female carriers of X-linked disease are often not pregnant on reproductive issues, or are at risk of giving birth to a male patient at risk of 1/2, and amniocentesis And fetal cell culture to determine the gender of the fetus, if male, most pregnant women carriers terminate the pregnancy, so lost 50% of normal fetal chances. The application of plasma Ⅷ C and Ⅸ factor prenatal diagnosis of hemophilia carriers pregnant women can give birth to normal healthy boys. Fetal blood samples were taken from 22 cases of gestational weeks 15 to 22 in direct vision fetus, and the plasma levels of Ⅷ C and Ⅸ were measured. The mean values ​​were 50 IU / dL (SD 12.8) and 12.5 IU / L (standard deviation 2.4). Of the 22 patients, 7 were diagnosed as potential carriers of hemophilia and 2 were intrauterine ones, highly assumed