目的调查北京市丰台区方庄社区70岁以上老年男性原发性骨质疏松症(OP)患病率及其相关的临床危险因素。方法根据入选和排除标准于2014年1—10月在北京市丰台区方庄社区采用广告招募的抽样方法,收集接受双能X线骨密度仪骨密度检查并完成《北京市老年男性原发性骨质疏松症高危人群临床危险因素调查问卷》调查的北京地区70岁以上老年男性人群150例。测量并记录所有患者的腰椎总(L1~4)、左侧股骨颈和左侧髋部总的骨密度值。根据WHO诊断标准诊断OP患者,将研究对象分为OP组和非OP组,分析各临床危险因素与OP发生的相关性。结果 150例老年男性OP患病率为20.7%(31/150),骨量减少者占55.3%(83/150),骨量正常者占24.0%(36/150)。150例老年男性腰椎总骨密度、左侧股骨颈骨密度、左侧髋部总骨密度比较,差异有统计学意义(F=96.106,P<0.001);其中腰椎总骨密度高于左侧股骨颈骨密度和左侧髋部总骨密度,左侧股骨颈骨密度高于左侧髋部总骨密度,差异均有统计学意义(P<0.001)。OP组和非OP组吸烟史、饮酒史、既往骨折病史、糖尿病史、饮茶、饮咖啡、饮碳酸饮料、食用醋情况比较,差异均无统计学意义(P>0.05);OP组和非OP组体质指数和体质量比较,差异有统计学意义(P<0.05)。以体质量评价OP时,AUC值为0.701,最佳诊断截断值为70.0 kg,灵敏度为48.7%,特异度为83.9%;以体质指数评价OP时,AUC值为0.661,最佳诊断截断值为23.8 kg/m2,灵敏度为62.2%,特异度为74.2%。结论方庄社区70岁以上老年男性OP患病情况不容忽视,低体质指数和低体质量是OP相关的临床危险因素,其中体质量因素有中度预测价值,但有待进一步深入研究。 Objective To investigate the prevalence of primary osteoporosis (OP) in elderly men over the age of 70 in Fangzhuang community of Fengtai district of Beijing and its related clinical risk factors. Methods According to the inclusion and exclusion criteria, we recruited a sampling method from January to October 2014 in Fangzhuang community of Fengtai district of Beijing to collect the data of BMD of dual-energy X-ray absorptiometry and complete the “ Osteoporosis high risk population risk factors survey questionnaire ”survey of 150 elderly men over the age of 70 in Beijing. All patients were measured and recorded total lumbar (L1 ~ 4), the left femoral neck and left hip total bone mineral density values. OP patients were diagnosed according to WHO diagnostic criteria, and the subjects were divided into OP group and non-OP group, and the correlation between each clinical risk factor and OP was analyzed. Results The prevalence of OP in 150 elderly men was 20.7% (31/150). The bone mass was decreased by 55.3% (83/150) and the normal bone mass was 24.0% (36/150). The total BMD of the lumbar spine, the femoral neck BMD of the left femur and the total BMD of the left hip in 150 elderly men were significantly different (F = 96.106, P <0.001). The BMD of the lumbar spine was higher than that of the left femur The bone mineral density of the left neck and neck, total bone mineral density of the left hip, left femur neck bone density higher than the total hip density of the left hip, the difference was statistically significant (P <0.001). There was no significant difference in smoking history, history of alcohol consumption, history of previous fracture, history of diabetes, drinking tea, drinking coffee, drinking carbonated drinks, edible vinegar in OP group and non-OP group (P> 0.05) There was significant difference between body mass index and body mass in OP group (P <0.05). The AUC value was 0.701, the best diagnostic cut-off value was 70.0 kg, the sensitivity was 48.7% and the specificity was 83.9%. The AUC value was 0.661 when the body mass index was used to evaluate OP. The best diagnostic cut-off value was 23.8 kg / m2, the sensitivity was 62.2% and the specificity was 74.2%. Conclusion The prevalence of OP in Fangzhuang community over the age of 70 can not be ignored. The low body mass index and low body mass are the clinical risk factors associated with OP. The body mass factors have moderate predictive values, but they are yet to be further studied.