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氟脲嘧啶栓是以聚乙二醇类为主的水溶性基质的栓剂,含量测定方法简单、可靠。体外溶出实验表明,释药快,T70=12.43min,毒性与直肠刺激试验未发现异常.
Fluorouracil suppository is a kind of suppository based on polyethylene glycol-based water-soluble matrix, the content determination method is simple and reliable. In vitro dissolution experiments showed that fast release, T70 = 12.43min, toxicity and rectal irritation test found no abnormalities.