论文部分内容阅读
目的:探讨米非司酮在妇科治疗中的应用前景。方法:终止妊娠时,研究组患者给予米非司酮配伍米索前列醇终止妊娠,对照组患者进行传统刮宫手术治疗。紧急避孕时,大剂量组患者给予25mg米非司酮进行紧急避孕,小剂量组患者给予10mg米非司酮进行紧急避孕。两组患者除米非司酮药物成分有所不同外,药片的性状、大小、颜色、气味等方面应完全相同。结果:米非司酮对患者进行终止妊娠时,在成功流产人数、不完全流产人数以及流产失败人数均无显著性差异的情况下,相较于传统手术终止妊娠患者具有出血量较少、住院时间较短以及并发症较少等优点。米非司酮用于紧急避孕时,大剂量组患者避孕有效率为89.71%,明显高于小剂量组患者有效率72.06%。结论:应用米非司酮不仅能进行终止妊娠和紧急避孕,还能够对患者出现的晚孕促宫颈成熟以及抗肿瘤等进行配合治疗,并具有较高的安全性和有效性。
Objective: To explore the prospect of mifepristone in gynecological treatment. Methods: At the termination of pregnancy, patients in study group were given mifepristone with misoprostol for termination of pregnancy and patients in control group were treated with conventional curettage. In emergency contraception, patients in the high-dose group received 25 mg of mifepristone for emergency contraception, and patients in the low-dose group received 10 mg of mifepristone for emergency contraception. In addition to the two groups of patients with different ingredients of mifepristone, the tablet traits, size, color, smell, etc. should be exactly the same. Results: Mifepristone patients with termination of pregnancy, the number of successful abortion, the number of incomplete abortion and the number of failed abortion cases, compared with the traditional surgical termination of pregnancy patients with less bleeding, hospitalization Shorter time and fewer complications. When mifepristone was used in emergency contraception, the effective rate of contraception in high-dose group was 89.71%, significantly higher than that in low-dose group (72.06%). Conclusion: The application of mifepristone not only can terminate the pregnancy and emergency contraception, but also can promote cervical ripening and anti-tumor therapy in the late pregnancy, and has high safety and effectiveness.