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1925年,Boas最先报告糖尿病患者可出现胃运动机能障碍。1945年,Rundles提出,其成因与植物神经功能障碍有很大关系。但Goyal和spiro认为,本病除了内脏植物神经功能障碍之外,造成消化道运动机能障碍的因素还有小血管损害,胰岛素或胰高血糖素分泌异常,血糖或电解质失衡,消化道的继发感染等原因。作者们的研究表明,植物神经功能障碍与胃的排空障碍有显著的相关关系。糖尿病患者之胃排空障碍,可出现恶心、呕吐、上腹不适、疼痛和食欲不振等症状。这些症状与血糖调节异常相关。当胃排空极端迟缓时,经口摄取的食物,吸收时间也大幅度延迟。
In 1925, Boas first reported diabetic patients may have gastric motility disorders. In 1945, Rundles proposed that its causes and autonomic dysfunction have a great relationship. However, Goyal and spiro that the disease in addition to visceral autonomic dysfunction, the factors that cause gastrointestinal motility disorders include small blood vessel damage, abnormal insulin or glucagon secretion, blood glucose or electrolyte imbalance, secondary to the digestive tract Infection and other reasons. Authors’ studies have shown that there is a significant correlation between autonomic dysfunction and gastric emptying disorder. Diabetic patients with gastric emptying disorders, nausea, vomiting, abdominal discomfort, pain and loss of appetite and other symptoms. These symptoms and abnormal glucose regulation. When the gastric emptying is extremely slow, the intake of food, oral absorption time is also significantly delayed.