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对鉴别非心源性胸痛,尚无有效的特殊试验。本文作者研究了高渗葡萄糖溶液对食管下端括约肌(LES)压力及食管收缩幅度的作用,并与其他激发试验进行对照。资料与方法:病人66例(平均年龄51岁)均经冠状动脉造影等方法排除冠状动脉疾病。16例健康对照组(平均年龄29岁),均为不吸烟者。受检病人取直立位,经口插入三腔导管,常规测压后,将导管末端开口置于LES上,通过连接三腔管的PE160导管灌注下列试验溶液: (1)0.9%氯化钠溶液,灌注速度4ml/min,共10min。 (2)0.1当量盐酸溶液,4ml/mn,共10min,如病人发现持续1min以上的疼痛即予停止。
To identify non-cardiac chest pain, there is no effective special test. The authors studied the effect of hypertonic glucose solution on the lower esophageal sphincter (LES) pressure and the amplitude of esophageal contractions and compared them with other excitation tests. Materials and Methods: 66 patients (mean age 51 years) were excluded coronary artery disease by coronary angiography. 16 healthy control group (mean age 29 years), all non-smokers. The patient under test was erected and inserted into a three-lumen catheter. After routine manometry, the end of the catheter was placed on the LES and the following test solutions were perfused through the PE160 catheter connected to the three-lumen tube: (1) 0.9% sodium chloride solution , Perfusion speed 4ml / min, a total of 10min. (2) 0.1 eq hydrochloric acid solution, 4ml / mn, a total of 10min, if the patient found that pain lasting more than 1min to stop.