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目的:探讨注意缺陷多动障碍(ADHD)患儿睡眠障碍与血清铁蛋白水平的关系。方法:符合美国精神疾病诊断与统计手册第4版(DSM-Ⅳ)中ADHD诊断标准的62例6-14岁ADHD患儿,由ADHD患儿的父母填写睡眠障碍量表(SDSC),检测ADHD患儿的血清铁蛋白水平。结果:与血清铁蛋白水平高于45μg/L的ADHD患儿相比较,血清铁蛋白水平低于45μg/L的ADHD患儿的SDSC“睡眠醒觉转换障碍”项评分和总分明显高于前者(P<0.05)。2组间其他项评分比较无显著性差异(P>0.05)。SDSC“睡眠醒觉转换障碍”项评分与血清铁蛋白水平成负相关(P<0.05)。结论:血清铁蛋白水平低于45μg/LADHD患儿SDSC“睡眠醒觉转换障碍”(睡眠中的异常运动)的危险性显著增加。
Objective: To investigate the relationship between sleep disorders and serum ferritin in children with attention deficit hyperactivity disorder (ADHD). Methods: Sixty-two children aged 6-14 years with ADHD diagnosed according to ADHD Diagnostic and Statistical Manual, Fourth Edition (DSM-IV) were enrolled in the Sleep Disorders Scale (SDSC) from parents of children with ADHD to detect ADHD Serum ferritin levels in children. Results: Compared with ADHD children whose serum ferritin level was higher than 45μg / L, SDSC ’s sleep-wake-transition disorder score and total score were significantly higher in ADHD children with serum ferritin level less than 45μg / L In the former (P <0.05). There was no significant difference between other two groups (P> 0.05). SDSC “sleep arousal ” score was negatively correlated with serum ferritin level (P <0.05). CONCLUSIONS: The risk of SDSC “sleep-wake-transition disorder ” (abnormal movement during sleep) in children with serum ferritin levels below 45 [mu] g / L ADHD is significantly increased.