睾丸精子抽取术(TESE)已经应用于严重的男性不育症的治疗,如非阻塞性的无精子症。近年TESE成功应用于非嵌合型Klinefelter综合征患者不育的治疗,这些患者睾丸小、伴性腺功能减低。非嵌合型Klinefelter综合征患者实施TESE时,采用常规多重睾丸活检技术,近年多应用微创TESE。微创T Testicular sperm extraction (TESE) has been used in the treatment of severe male infertility, such as non-obstructive azoospermia. In recent years, TESE has been successfully used in the treatment of infertility in patients with non-chimeric Klinefelter syndrome. These patients have small testicles with reduced gonadal function. Non-chimeric Klinefelter syndrome in the implementation of TESE, the use of conventional multiple testicular biopsy techniques in recent years, more applications of minimally invasive TESE. Minimally invasive T