肾小球疾病的诊断技术可以区分为创伤性及非创伤性两大类。大约从六十年代开始,国际上即常规地依靠创伤性检查(肾活检)诊断肾小球疾病,习惯于根据组织形态学进行分型,对非创伤性诊断比较忽视。肾小球疾病的组织学分型在诊断预后及指导治疗上确有一定价值,对推动肾小球疾病研究工作的发展有重要意义。然而不可否认单纯组织学分型也存在 The diagnosis of glomerular disease can be divided into traumatic and non-invasive two major categories. About 60 years from the beginning, the international routinely rely on traumatic examination (renal biopsy) diagnosis of glomerular disease, accustomed to classification based on histological morphology, non-invasive diagnosis of neglect. Histopathological type of glomerular disease in the diagnosis of prognosis and guiding treatment has a certain value, to promote the development of glomerular disease research is of great significance. However, it is undeniable that histological typing also exists