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本文测定了用Zn与Cu饲养的老年大鼠、老年对照大鼠的血清溶菌酶、抗绵羊红细胞抗体、脾脏抗体形成细胞(PFC)、E—花环形成、血浆淋巴细胞酯酶(ANAE)阳性率。血清总抗氧化活性与红细胞内SOD活性等。结果表明,老年大鼠除血清溶菌酶活性与成年大鼠相近外,其余各项指标均明显低于成年大鼠。经给Zn与Cu饲养后的老年大鼠,上述所有指标均明显高于老年对照大鼠。提示Zn与Cu可恢复老年大鼠的免疫功能和提高血清总抗氧化活性与红细胞内SOD活性而有抗衰老效应。
In this study, serum lysozyme, anti-sheep erythrocyte antibody, spleen antibody-forming cells (PFC), E-wreck formation, and plasma lymphocyte esterase (ANAE) positive rate were measured in aged rats and old control rats fed with Zn and Cu. . Serum total antioxidant activity and red cell SOD activity. The results showed that, except for serum lysozyme activity in aged rats, similar to adult rats, all other indicators were significantly lower than those in adult rats. After aging Zn and Cu in the aged rats, all the above indicators were significantly higher than the old control rats. It is suggested that Zn and Cu can restore the immune function of aged rats and increase the total anti-oxidation activity of serum and the activity of SOD in erythrocytes but have anti-aging effects.