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目的 观察火针疗法联合积雪苷片治疗中重度痤疮的疗效及安全性.方法 124例中、重度痤疮患者,随机分为治疗组与对照组各62例,两组均采用火针局部治疗,治疗组加服积雪苷片.在治疗4周、8周后评估两组的疗效及不良反应.结果 治疗组与对照组4周、8周后有效率分别为80.6％和62.9％、98.4％和80.6％,治疗组有效率比对照组高,差异有统计学意义(P＜0.05),且不良反应少.结论 火针联合积雪苷片治疗中重度痤疮是一种疗效好、安全性高的治疗方法,可供临床选用.“,”Objective To observe the clinical efficacy and safety of fire needle combined with centella triterpenes tablet in treatment of moderate to severe acne.Methods 124 cases of patients with moderate to severe acne were randomly divided into treatment group and control group,62 cases in each group.Treatment group was treat with oral administration of centella triterpenes tablet combined with the local fire needle;control group received local fire needle treatment.The efficacies and adverse reactions of the two groups were assessed at the end of the 4th and the 8th weeks.Results The effective rates of treatment group and control group was 80.6 ％ and 62.9％,98.4％ and 80.6％ at the end of the 4th and the 8th weeks respectively,treatment group was higher than control group,the difference was statistically significant (P＜0.05),and fewer adverse reactions occured in treatment group.Conclusion Centella triterpenes tablet combined with fire needle is an effective and safe method in treatment of moderate to severe acne,which is worthy of clinical promotion.