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目的:采用星点设计-效应面法优选消疮凝胶剂的提取工艺。方法:以乙醇倍量、乙醇浓度和提取时间为主要影响因素,以大黄素、大黄酚的含量和浸膏得率为评价指标,用星点设计-效应面法优选消疮凝胶剂的提取工艺。结果:最佳提取工艺为:加入10倍量60%乙醇溶液,提取2次,每次2h。结论:采用星点设计-效应面法优选消疮凝胶剂的提取工艺方法简便,预测性好。
OBJECTIVE: To optimize the extraction process of desquamating gel by the method of star point design-response surface method. Methods: Taking ethanol concentration, ethanol concentration and extraction time as the main influential factors, taking the content of emodin and chrysophanol and the yield of extract as the evaluation indexes, the star spot design-response surface method was used to optimize the extraction of desquamating gel Process. Results: The best extraction process was: adding 10 times the amount of 60% ethanol solution, extracted twice, each time 2h. Conclusion: The method of star design - response surface optimization of descaling gels extraction method is simple and predictive.