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本文对256名连续服用国产1号避孕片5～24年的健康农村妇女,及288名同期使用宫内节育器的妇女脂代谢水平进行研究。结果表明,长期用口服避孕药(OC)妇女血清甘油三脂(TG)、总胆固醇(TCh)、高密度脂蛋白(HDL)及其亚组(HDL_2,HDL_3)和低密度脂蛋白(LDL)水平均有所升高。TG 在35岁以下,连续服药不足15年的人群中呈极显著增高(P<0.01),而 TCh 和HDL 则在35岁以上,连续服药15年以上的人群中才有极显著增高(P<0.01)。LDL 的增高在各组均未达到显著性水平(P>0.05),HDL/LDL 值在各年龄组和不同使用时间分组中较稳定。
In this paper, 256 healthy rural women who took domestic contraceptive pill 1 for 5-24 years continuously and 288 women who used IUD for the same period were studied on lipid metabolism. The results showed that serum triglyceride (TG), total cholesterol (TCh), high density lipoprotein (HDL) and its subgroups (HDL_2, HDL_3) and low density lipoprotein (LDL) The level has risen. TG was significantly higher in those below 35 years of age with less than 15 years of continuous medication (P <0.01), while TCh and HDL were significantly higher in those over 35 years of age with more than 15 years of continuous medication (P < 0.01). LDL increased in each group did not reach the significant level (P> 0.05), HDL / LDL values in all age groups and different use time group more stable.