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为观察黑芝麻、白芝麻、燕麦对发育期小鼠血脂及脂质过氧化作用的影响,用各含有10%上述食品的三种饲料分别喂问离乳小鼠6周,测定血清总胆固醇(TC)、血清高密度脂蛋白胆固醇(HDL-C)及肝、肾、脑组织中的脂质过氧化产物丙二醛(MDA)、还原型谷胱甘肽(CSH)的含量,计算高密度脂蛋白胆固醇与总胆固醇的比值(HDL-C/TC)、动脉硬化指数(AI)。结果表明,与对照组相比,各实验组小鼠血中TC、HDL-C、HDL-C/知及AI值的差别均无显著性(P>0.05);各实验组肝脏组织中MDA的含量明显低于对照组,其差别有显著性(P<0.01);黑芝麻织、白芝麻组脑组织中MDA的含量也明显低于对照组,差别有显著性(P<0.05);各实验组肾脏组织中GSH的含量明显高于对照组,其差别有显著性(P<0.01),说明黑芝麻、白芝麻及燕麦可以提高小鼠机体的抗脂质过氧化能力。
To observe the effects of black sesame seeds, white sesame seeds and oats on blood lipid and lipid peroxidation in developing mice, the three kinds of feed containing 10% of the above foods were respectively fed to the mice for 6 weeks to determine the serum total cholesterol (TC), serum high density lipoprotein cholesterol (HDL-C), malondialdehyde (MDA) and reduced glutathione (CSH) in liver, Lipoprotein cholesterol to total cholesterol ratio (HDL-C / TC), arteriosclerosis index (AI). The results showed that compared with the control group, there was no significant difference in TC, HDL-C, HDL-C / AI and AI between the experimental groups (P> 0.05) MDA content was significantly lower than the control group, the difference was significant (P <0.01); black sesame seeds and white sesame group brain MDA content was significantly lower than the control group, the difference was significant (P <0 .05). The contents of GSH in kidney tissue in each experimental group were significantly higher than those in control group (P <0.01), indicating that black sesame seeds, white sesame seeds and oats can improve the anti-lipid Oxidation ability.