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目的:分析肿瘤外科住院患者围术期抗菌药物的使用情况,评价抗菌药物使用的合理性,为促进临床合理用药提供依据。方法:对2011年1月~2014年2月杭州市第一人民医院肿瘤外科手术治疗的62例患者的临床资料进行回顾性分析。结果:调查对象共62例,抗菌药物使用率为100%,用药次数为102例次。其中,头孢哌酮使用频率最高,其他依次为头孢地嗪、头孢他啶、左氧氟沙星、奥硝唑、克雷霉素、哌拉西林/舒巴坦钠;术前抗菌药物合理使用率为93.55%;手术时间<3小时的术中抗菌药物合理率为100%,手术时间>3小时的术中抗菌药物合理率为84.62%;术后抗菌药物合理使用率为83.87%。结论:应加强肿瘤外科围术期患者抗菌药物合理使用,保证患者用药安全。
OBJECTIVE: To analyze the use of perioperative antibiotics in inpatients with oncology surgeries and to evaluate the rationality of antibacterials’ use and to provide basis for promoting clinical rational drug use. Methods: The clinical data of 62 patients who underwent surgical treatment of tumor in First People’s Hospital of Hangzhou from January 2011 to February 2014 were retrospectively analyzed. Results: A total of 62 subjects were surveyed, the antibacterial drug use rate was 100%, and the frequency of medication was 102 cases. Among them, cefoperazone had the highest frequency of use, followed by cefodizime, ceftazidime, levofloxacin, ornidazole, crylomycin and piperacillin / sulbactam sodium. The rational use rate of preoperative antibiotics was 93.55% The reasonable rate of intraoperative antibacterials within 3 hours was 100%, the reasonable rate of intraoperative antibiotics within 3 hours after operation was 84.62%, and the rational use of antibacterials after operation was 83.87%. Conclusion: The rational use of antimicrobial agents in perioperative patients should be strengthened to ensure the safety of patients.