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本文报告39例肝硬化患者血浆肾素、血管紧张素Ⅱ及醛固酮(RAA)测定结果。分为3组:第1组18例,无腹水;第2组13例,轻至中度腹水;第3组9例,重度腹水。第1、2组与对照组之间无显著差异,第3组则显著升高,且有统计学意义。在三组之间,血浆肾素平均值随腹水严重程度而呈相关关系,以第3组更为显著;血管紧张素Ⅱ在第3组虽有增高,但无统计学意义;醛固酮均值则随腹水严重程度而增高,并有显著差异,提示肝硬化重度腹水与RAA系统活跃有关。
This article reports the results of plasma renin, angiotensin II and aldosterone (RAA) measurements in 39 patients with cirrhosis. Divided into 3 groups: Group 1 18 cases, no ascites; Group 2 13 cases, mild to moderate ascites; Group 3 9 cases, severe ascites. There was no significant difference between the first and second groups and the control group, the third group was significantly increased, and there was statistical significance. Among the three groups, the mean value of plasma renin correlated with the severity of ascites and was more significant in group 3. Angiotensin II was increased in group 3 but not statistically significant. The mean of aldosterone was The severity of ascites and increased, and significant differences, suggesting that cirrhosis and severe ascites RAA system is active.