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本文首次报告1例Wilson’s病合并甲旁亢。 患者男性,18岁,15个同胞兄弟中4人患者有Wilson’s病。2岁时测得血清铜蓝蛋白为0.27g/L,11岁时逐渐出现怠倦,不能胜任同龄儿童的运动量。查体肝脏轻度肿大、质硬,边缘不规则,脾脏中度肿大,中度腹水,双躁部凹陷性水肿,血清铜蓝蛋白0.20g/L,23小时尿铜排泄5.5mmol,血浆白蛋白31g/L,球蛋白38g/L,天门冬氨酸氨基转移酶活性58g/L,角膜有kayser-Fleischer环,凝血酶原比值1.7,血小板计数122×10~3,血钙2.16mmol/L,1988年已经有大量腹水和严重的
This is the first report of a Wilson’s disease with hyperparathyroidism. Patient Male, 18 years old, 4 out of 15 siblings have Wilson’s disease. 2-year-old measured serum ceruloplasmin was 0.27g / L, 11-year-old gradual emergence of fatigue, can not do the same amount of exercise for children of the same age. Check the body of the liver mild swelling, hard, irregular edges, moderate spleen enlargement, moderate ascites, biphasic depression edema, serum ceruloplasmin 0.20g / L, 23 hours of urinary copper excretion 5.5mmol, plasma Albumin 31g / L, globulin 38g / L, aspartate aminotransferase activity 58g / L, corneal kayser-Fleischer loop, prothrombin ratio 1.7, platelet count 122 × 10 ~ 3, blood calcium 2.16mmol / L, already had a lot of ascites and serious in 1988