目的探讨和分析早期应用药物治疗慢性呼吸衰竭并发肺性脑病的临床效果,总结其临床价值。方法回顾性分析具有完整临床资料的2009年10月至2011年10月来我院就诊的慢性呼吸衰竭并发肺性脑病患者40例,随机分为观察组和对照组两组,每组患者有20例。两组患者均进行抗感染治疗,并给予吸氧、止咳化痰、平喘、维持水和酸碱电解质平衡治疗,观察组在此基础上给予氟哌啶醇进行治疗。结果按制定的标准评价治疗慢性呼吸衰竭并发肺性脑病的临床疗效。对照组显效3例,有效11例,无效6例,总有效率为70.00%。观察组显效6例,有效12例,无效2例,总有效率为90.00%。经χ2检验,两组疗效差异有统计学意义(P<0.05),观察组疗效优于对照组。结论早期应用药物治疗慢性呼吸衰竭并发肺性脑病具有较好的临床疗效。是治疗慢性呼吸衰竭并发肺性脑病的有效方法之一,具有较好的临床价值,值得临床借鉴和推广。 Objective To investigate and analyze the clinical effects of early application of drugs in treating chronic respiratory failure complicated with pulmonary encephalopathy and to summarize its clinical value. Methods A retrospective analysis of 40 patients with chronic respiratory failure and pulmonary encephalopathy admitted to our hospital from October 2009 to October 2011 with complete clinical data was randomly divided into observation group and control group, with 20 cases in each group example. Two groups of patients were anti-infective treatment, and given oxygen, relieving cough and phlegm, asthma, water and acid-base electrolyte balance treatment, the observation group on the basis of haloperidol treatment. Results According to the established standards for the evaluation of clinical efficacy of treatment of chronic respiratory failure complicated with pulmonary encephalopathy. The control group was markedly effective in 3 cases, effective in 11 cases, ineffective in 6 cases, the total effective rate was 70.00%. In the observation group, 6 cases were markedly effective, 12 cases were effective, 2 cases were ineffective, and the total effective rate was 90.00%. By χ2 test, the difference between the two groups was statistically significant (P <0.05), the observation group was better than the control group. Conclusion Early application of drug treatment of chronic respiratory failure with pulmonary encephalopathy has a good clinical effect. It is one of the effective methods to treat chronic respiratory failure complicated with pulmonary encephalopathy. It has good clinical value and is worthy of clinical reference and promotion.