ras P_(21)是ras癌基因族的产物。为探索抗rasP_(21)单克隆抗体(简称P_(21)单抗)临床应用的可能性及肿瘤的癌变机理,作者通过ABC免疫试验和免疫印迹试验,用我室研制的P_(21)单抗SCI-oncogemaI分析了约137例人肿瘤组织和正常组织的ras P_(21)表达。 材料和方法 一、标本的组织类型 原发性肺癌38例,其中腺癌19例、鳞癌15例、未分化癌4例(其中小细胞 Ras P_(21) is a product of the ras oncogene family. To explore the possibility of clinical application of anti-rasP_(21) monoclonal antibody (abbreviated as P_(21) monoclonal antibody) and the mechanism of tumor carcinogenesis, the authors used the P_(21) sheet developed by our laboratory through ABC immunoassay and Western blotting experiments. Anti-SCI-oncogemaI analysis of ras P_(21) expression in about 137 human tumor tissues and normal tissues. Materials and Methods 1. Tissue types of specimens 38 primary lung cancers, including 19 adenocarcinomas, 15 squamous cell carcinomas, and 4 undifferentiated carcinomas (small cells among them)