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目的:观察阿托伐他汀联合厄贝沙坦治疗高血压左心室肥厚的临床疗效,以供临床工作参考。方法:选择我院收治的高血压左心室肥厚患者70例,随机分为对照组和观察组各35例。全部患者均给予厄贝沙坦治疗,观察组患者在此基础上给予阿托伐他汀治疗,连续治疗6个月,观察并比较两组患者治疗前后血压水平和左心室质量指数的差异。结果:与治疗前比较,两组患者血压水平均有下降(P<0.05),组间比较差异无统计学意义(P>0.05)。与治疗前比较,两组患者左心室质量指数均有不同程度的下降,其中观察组的改善程度明显优于对照组,差异有统计学意义(P<0.05)。结论:采用阿托伐他汀联合厄贝沙坦治疗高血压左心室肥厚,可以取得较满意的临床疗效,值得推广应用。
Objective: To observe the clinical efficacy of atorvastatin combined with irbesartan in the treatment of left ventricular hypertrophy of hypertension for clinical reference. Methods: Seventy patients with hypertensive left ventricular hypertrophy admitted to our hospital were randomly divided into control group and observation group of 35 cases. All patients were treated with irbesartan. Patients in the observation group were given atorvastatin on this basis for 6 months. The differences of blood pressure and left ventricular mass index before and after treatment were observed and compared between two groups. Results: Compared with those before treatment, the blood pressure of both groups decreased (P <0.05). There was no significant difference between the two groups (P> 0.05). Compared with pre-treatment, left ventricular mass index decreased in both groups, and the improvement in observation group was better than that in control group, the difference was statistically significant (P <0.05). Conclusion: Atorvastatin combined with irbesartan in the treatment of hypertensive left ventricular hypertrophy can achieve more satisfactory clinical efficacy, which is worth popularizing and applying.