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目的通过对我科确诊的4例细小病毒B19(parvovirus B19)关节炎的临床特点的总结,提高对该病的认识。方法报道4例确诊为细小病毒B19关节炎的临床及实验室检查特点,并进行文献复习。结果4例患者(男性2例,女性2例),年龄15~55岁,发病年龄中位数为34岁。关节炎同时出现流感样症状、皮疹等表现,外周血细小病毒B19 IgM均阳性,3例患者外周血细小病毒B19DNA检测阳性.除外其他原因所致关节炎.治疗效果肯定,随访1~3年无一例复发。结论对于某些症状不典型的关节炎,应警惕细小病毒B19关节炎的可能,及时行细小病毒B19抗体及DNA检测,以助诊断。
Objective To improve the understanding of the disease by summarizing the clinical features of 4 parvovirus B19 arthritis diagnosed in our department. Methods Four cases of clinical and laboratory examination of parvovirus B19 arthritis were reported and reviewed. Results Four patients (2 males and 2 females) aged 15-55 years and median age at onset were 34 years old. Arthritis at the same time flu-like symptoms, rash and other performance, peripheral blood parvovirus B19 IgM were positive, 3 patients with peripheral blood parvovirus B19DNA positive. Except for other causes of arthritis. The treatment was positive, followed up for 1 to 3 years A case of recurrence. Conclusion For some of the symptoms of atypical arthritis, should be wary of the possibility of parvovirus B19 arthritis, timely detection of parvovirus B19 antibodies and DNA to help diagnose.