在认识促进动脉粥样硬化的因素中已有很多有价值的临床研究资料,但血管损害的发病机理仍不清楚。近十年来进行的研究提出血管壁的平滑肌和内皮细胞分泌和产生的物质在动脉粥样硬化的发生和发展中有很重要的作用。另外在血管内壁的内皮细胞与血液动力的影响和许多血液成分(血小板、脂蛋 There are many valuable clinical studies in understanding the factors that promote atherosclerosis, but the pathogenesis of vascular damage remains unclear. Studies conducted over the past decade suggest that substances secreted and produced by vascular smooth muscle and endothelial cells play an important role in the development and progression of atherosclerosis. In addition, the endothelial cells in the inner wall of blood vessels are associated with hemodynamic effects and many blood components (platelets,