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目的:观察华蟾素对晚期恶性肿瘤患者T淋巴细胞亚群及NK细胞的影响。方法:将321例晚期恶性肿瘤患者随机分为治疗组202例和对照组119例,治疗组在对照组基础上加用华蟾素注射液治疗。观察两组患者T淋巴细胞亚群及NK细胞变化情况。结果:华蟾素治疗组患者的T淋巴细胞亚群和NK细胞显著提高(P<0.05)。结论:华蟾素对晚期恶性肿瘤患者有提高免疫力、抑制肿瘤细胞活性的作用。
Objective: To observe the effect of cinobufacini on T lymphocyte subsets and NK cells in patients with advanced malignant tumors. Methods: A total of 321 patients with advanced malignant tumor were randomly divided into treatment group (n = 202) and control group (n = 119). The treatment group was treated with cinobufacini injection on the basis of the control group. The changes of T lymphocyte subsets and NK cells in two groups were observed. Results: The T lymphocyte subsets and NK cells of cinobufotalin treatment group were significantly increased (P <0.05). Conclusion: Cinobufacini can improve immunity and inhibit tumor cell activity in patients with advanced malignant tumors.