阿司匹林能延长皮肤出血时间是由于它导致血小板功能异常,服阿司匹林后的胃出血被认为是由于胃出血时间延长。为了确定服阿司匹林的患者做内窥镜活检是否安全,作者对4组患者研究了快速和缓慢应用阿司匹林对胃出血时间的影响。在内窥镜活检后直接测定胃出血时间,另以 Mielke 法测定皮肤出血时间。第1组为10名正常人,相隔1周进行2次检查,确定内窥镜检出血时间在技术上的可重复性;第2组为10名正常人,口服阿司匹林650mg,每天4次,共24h,于服药前、后进行研究;第3组为5名正 Aspirin can prolong the bleeding time of the skin because it causes abnormal platelet function. Gastric bleeding after aspirin administration is considered to be due to an extended period of gastric bleeding. In order to determine if endoscopic biopsy is safe for aspirin-treated patients, the authors studied the effect of aspirin on gastric hemorrhage in four groups of patients. In the endoscopic biopsy directly after the determination of gastric bleeding time, the other with Mielke method of skin bleeding time. The first group of 10 normal subjects, 1 week apart 2 times to determine the technical endoscopy time of blood was reproducible; the second group of 10 normal people, oral aspirin 650mg, 4 times a day, a total of 24h, before taking medicine, after the study; the third group of five positive