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目的：加强广东省登革热的监测，防止该病的大流行。方法：收集发烧可疑患者的血标本及蚊子标本作病原分离，并进一步用ＲＴ－ＰＣＲ鉴定；采集监测点健康人血标本，应用间接免疫荧光试验作抗体水平调查。结果：在佛山、沙湾、坪石３个监测点收集的发热待查患者和蚊媒标本，均未分离出登革病毒。蚊媒监测结果表明：布雷图指数大大超过有效控制指标５；全年大部分时间布雷图指数均超过２０以上；血清学调查表明：健康人群抗体水平逐年下降。结论：存在登革热暴发流行的潜在危险。
Objective: To strengthen the monitoring of dengue fever in Guangdong Province to prevent the pandemic. Methods: Blood samples and mosquito specimens from patients with fever were collected for pathogen isolation and further identified by RT-PCR. Blood samples were collected from healthy volunteers and antibody levels were measured by indirect immunofluorescence assay. Results: The Dengue virus was not isolated from the fever patients and the mosquito media collected from 3 monitoring sites in Foshan, Shawan and Pingshi. The mosquito media monitoring results showed that: the Bretti’s index greatly exceeded the effective control index 5; the Brettii index exceeded 20 for most of the year; and the serological survey showed that the antibody level of the healthy population declined year by year. Conclusion: There is a potential risk of dengue outbreaks.