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目的观察食醋灌肠治疗肝性脑病(HE)的疗效。方法将68例(HE)患者随机分为治疗组和对照组。两组均给予护肝、去氨等常规综合治疗措施,治疗组加用食醋灌肠治疗。观察并对比两组患者治疗后的临床疗效、清醒时间和治疗前后的血氨、肝功能变化等情况。结果治疗组总有效率94.4%,对照组总有效率75%,组间比较,差异有统计学意义(P<0.01),治疗组平均清醒时间(18.2±4.5)h,对照组平均清醒时间(26.7±5.6)h,组间比较,差异有统计学意义(P<0.05)。治疗组TBIL和NH3的降低较对照组明显(P<0.05)。结论食醋灌肠治疗HE可提高疗效,且费用低廉,为临床上治疗HE的有效辅助治疗方法之一。
Objective To observe the curative effect of vinegar enema on hepatic encephalopathy (HE). Methods 68 patients (HE) were randomly divided into treatment group and control group. Both groups were given routine treatment of liver, ammonia and other conventional treatment, the treatment group plus vinegar enema treatment. Observed and compared two groups of patients after treatment of clinical efficacy, awake time and before and after treatment of blood ammonia, liver function changes and so on. Results The total effective rate was 94.4% in the treatment group and 75% in the control group. The difference between the two groups was statistically significant (P <0.01), the mean awake time (18.2 ± 4.5) h in the treatment group and the average awake time in the control group 26.7 ± 5.6) h, the difference between the two groups was statistically significant (P <0.05). The reduction of TBIL and NH3 in the treatment group was more significant than that in the control group (P <0.05). Conclusion The treatment of HE with vinegar enema can improve the curative effect and the cost is low, which is one of the effective adjuvant therapy for the clinical treatment of HE.