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随着围产医学的发展,如何降低围产儿的死亡,已是当前围内、外非常重视的问题。在国产儿死亡中早产儿较足月新生儿死亡率明显升高。为降低早产儿的出生,国外对胎儿成熟度测定的研究已有不少报道,近年来国内亦有报道,现将测定胎儿成熟度的方法综述如下。一、测定胎儿肺成熟度胎儿肺泡的成熟,主要由于肺表面活性物质的存在,这种活性物质为复杂的蛋白和磷脂的合成物。磷脂中有卵磷脂(Lecithin)和鞘磷脂(Sphingomyelin)。磷脂随孕期而增加,因而可测定胎儿成熟情况。测定方法: (一)卵磷脂浓度测定:Nelson氏(1972)报道了测定羊水中卵磷脂的浓度作为观察
With the development of perinatal medicine, how to reduce the death of perinatal children has become a very important issue in and out of the area. Mortality in domestic children than full-term neonatal mortality was significantly higher. In order to reduce the birth of premature babies, foreign studies on fetal maturity have been reported in many countries in China. The methods for determining fetal maturity are summarized as follows. First, determine the fetal lung maturity Fetal alveolar maturity, mainly due to the presence of pulmonary surfactant, this active substance is a complex protein and phospholipid complexes. Phospholipids are lecithin and sphingomyelin. Phospholipid increases with pregnancy, which can determine fetal maturity. Determination: (a) Determination of lecithin concentration: Nelson’s (1972) reported the determination of amniotic fluid lecithin concentration as observed