回顾6例类风湿性关节炎所致角膜边缘溶解症,其中3例类风湿性关节炎改变明显;另3例虽无明显的关节炎改变,但其血清类风湿因子为阳性。角膜边缘的改变主要为基质溶解,表现为角膜变薄,甚至穿孔,病变区有新生血管形成。施行板层角膜边缘移植术或结膜辨遮盖术后,可发生再溶解而致视力丧失。术后局部应用免疫抑制剂环胞霉素,可获得一定的疗效。 Review of 6 cases of rheumatoid arthritis caused by corneal edge lysis, of which 3 cases of rheumatoid arthritis changed significantly; the other 3 cases although no significant changes in arthritis, but the serum rheumatoid factor was positive. Corneal changes in the main edge of the matrix is ​​dissolved, the performance of the corneal thinning, or even perforation, the lesion area of ​​neovascularization. After the implementation of lamellar corneal limbal transplantation or conjunctival discernment, re-dissolution may occur and cause loss of vision. Postoperative local application of immunosuppressive agents cyclosporine, can obtain a certain effect.