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当环孢素(Cs)同时与其它肾毒性药物并用时可产生相互作用,使Cs的血浓度改变或产生毒性作用。Cs—药物间相互作用的可能机理主要影响肠道淋巴流和胆汁流、脂蛋白结合力、肝脏代谢
Cyclosporine (Cs) can interact with other nephrotoxic drugs at the same time to change the blood concentration of Cs or cause toxic effects. The possible mechanism of Cs-drug interactions mainly affects intestinal lymph flow and biliary flow, lipoprotein binding, liver metabolism