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目的观察甲泼尼龙琥珀酸钠治疗毛细支气管炎的临床疗效。方法将88例毛细支气管炎患儿随机分为治疗组42例和对照组46例。对照组给予综合治疗(抗感染、平喘、对症治疗等),治疗组在综合治疗的基础上加用甲泼尼龙琥珀酸钠平喘治疗。对比2组临床疗效和咳嗽、气促、喘鸣音及湿啰音消失时间。结果治疗组总有效率明显高于对照组(P<0.05)。治疗组咳嗽、气促、喘鸣音和湿啰音消失时间短于对照组(P<0.05)。结论甲泼尼龙琥珀酸钠治疗毛细支气管炎疗效显著。
Objective To observe the clinical efficacy of methylprednisolone sodium succinate in the treatment of bronchiolitis. Methods Eighty-eight children with bronchiolitis were randomly divided into treatment group (n = 42) and control group (n = 46). The control group was given comprehensive treatment (anti-infective, asthma, symptomatic treatment, etc.), the treatment group in combination with methylprednisolone sodium succinate on the basis of asthma treatment. The clinical efficacy and cough, shortness of breath, wheezing and wet rales disappeared in two groups. Results The total effective rate of the treatment group was significantly higher than that of the control group (P <0.05). The treatment group cough, shortness of breath, wheezing and wheezing disappeared shorter than the control group (P <0.05). Conclusion The efficacy of methylprednisolone succinate in the treatment of bronchiolitis is significant.