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冠状动脉粥样硬化性心脏病(冠心病)已成为当今严重危害人类健康、影响人们生活质量的最常见心血管疾病病之一。冠心病的形成是多种危险因素共同作用的结果。亚临床甲状腺功能减退症(subclinical hypothyroidism,SH)在一般人群中的患病率为3%～8%,并与年龄呈正相关,在60岁以上妇女中可达20%,65岁以上的男性患病率与女性接近。SH可隐蔽与持续地造成靶组织及靶器官损害,它是动脉粥样硬化的元凶。现将SH与冠心病的发生及发展的相关性作一综述。
Coronary atherosclerotic heart disease (CHD) has become one of the most common cardiovascular diseases that seriously endanger human health and affect people’s quality of life today. Coronary heart disease is the result of a combination of risk factors. The prevalence of subclinical hypothyroidism (SH) in the general population is between 3% and 8% and is positively correlated with age, with up to 20% among women over the age of 60 and over 65 The rate is close to that of women. SH can conceal and continue to cause damage to target tissues and target organs, it is the culprit of atherosclerosis. Now SH and the occurrence and development of coronary heart disease are reviewed.