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对某石棉制品厂接触石棉工人进行了剂量-反应关系的调查研究。各作业场所石棉粉尘的各时期的重量浓度用另文所介绍的转换方法换算成计数浓度。对工人的职业史作了详细记录。石棉肺病例根据职业史及胸片诊断。患者的接触剂量系用换算得的计数浓度乘其接触时间,并累加至诊断为Ⅰ期石棉肺之日止,其余工人的接触剂量则加至1982年9月止。用寿命表法建立了石棉纤维计数浓度的剂量-反应关系。据此,可预测3％的石棉肺患病率时,接触剂量相应为43根·年,以工人一生工作35年计,相当于空气中石棉纤维浓度1.22根/ml。建议以1.2根/ml为车间空气中石棉尘的计数浓度卫生标准。
Investigate the dose-response relationship of asbestos workers exposed to asbestos products factory. The weight concentration of asbestos dust at each work site for each period was converted to the counting concentration by the conversion method described elsewhere. Occupational history of workers made a detailed record. Asbestosis cases according to occupational history and chest X-ray diagnosis. The patient’s exposure dose was calculated by multiplying the calculated count concentration by the contact time and adding to the date of the diagnosis of stage I asbestosis, with the remainder of the dose added to September 1982. A dose-response relationship of asbestos fiber count concentration was established using the life table method. Accordingly, the prevalence of asbestosis in 3% of the lungs can be predicted at a corresponding exposure dose of 43 roots / year and 35 days in a worker’s life, corresponding to 1.22 asbestos fibers in air. It is recommended to 1.2 root / ml for the workshop air asbestos dust count concentration of health standards.