14例证实为子宫内膜异位症及腺肌症患者应用 Gn RH- a 3.6 m g皮下埋植 ,4周 1次 ,连续 6次 ,用放射免疫法测定血促卵泡素 (FSH)、黄体生成素 (L H)、泌乳素 (PRL )、雌二醇 (E2 )及孕激素 (P)水平。结果表明患者在治疗期间均闭经 ,症状明显改善 ,卵巢巧克力囊肿明显缩小至消失 ,子宫肌腺症几近消失 ,副作用主要有潮热、阴道干燥等 ,其中 6例经联合激素反加疗法后减轻至消失。骨密度下降 4%。 Fourteen patients confirmed endometriosis and adenomyosis were treated with Gn RH- a 3.6 mg implanted subcutaneously once every 4 weeks for 6 consecutive times. The levels of serum FSH, luteinizing hormone (FSH) LH, PRL, E2 and progesterone (P). The results showed that during the treatment of patients with amenorrhea, symptoms were significantly improved, ovarian chocolate cyst significantly reduced to disappear, uterine adenomyosis almost disappeared, the main side effects of hot flashes, vaginal dryness, of which 6 cases were combined with hormone regimen To disappear. Bone density decreased by 4%.