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目的分析ICU住院患者尿培养的菌群分布情况及抗生素耐药性。方法分析ICU住院患者尿培养的菌群分布情况及病原菌药敏试验结果。结果选择的235例ICU住院患者,尿培养共检出162株病原菌,其中革兰阴性菌98株(60.49%)、革兰阳性菌45株(27.78%)、真菌19株(11.73%)。革兰阴性菌中检出率较高的主要是大肠埃希菌、肺炎克雷伯菌、阴沟肠杆菌、铜绿假单胞菌及鲍氏不动杆菌;革兰阳性菌中检出率较高的主要是肠球菌、链球菌及金黄色葡萄球菌。革兰阴性杆菌的主要敏感药物是亚胺培南、美洛培南、哌拉西林/他唑巴坦、阿米卡星及头孢哌酮/舒巴坦,革兰阳性球菌的主要敏感药物有万古霉素,替考拉宁,呋喃妥因,利福平。结论 ICU住院患者尿培养常见的致病菌为革兰阴性菌,主要敏感药物为亚胺培南、美洛培南、哌拉西林/他唑巴坦等。
Objective To analyze the flora distribution and antibiotic resistance of urinary culture in hospitalized patients in ICU. Methods The distribution of bacteria in urine culture of inpatients with ICU and drug susceptibility test results of pathogens were analyzed. Results Among the 235 ICU inpatients selected, 162 pathogens were found in urine culture, of which 98 (60.49%) were Gram-negative, 45 (27.78%) were Gram-positive and 19 (11.73%) were fungi. Escherichia coli, Klebsiella pneumoniae, Enterobacter cloacae, Pseudomonas aeruginosa and Acinetobacter baumannii were detected mainly in the Gram-negative bacteria. The detection rate in Gram-positive bacteria was high The main is Enterococcus, Streptococcus and Staphylococcus aureus. The main sensitive drugs of gram-negative bacilli are imipenem, meropenem, piperacillin / tazobactam, amikacin and cefoperazone / sulbactam. The main sensitive drugs of gram-positive cocci are Vancomycin, teicoplanin, nitrofurantoin, rifampicin. Conclusion The common pathogenic bacteria in urinary culture of inpatients in ICU are Gram-negative bacteria. The main sensitive drugs are imipenem, meropenem, piperacillin / tazobactam and so on.