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目的探讨药物流产后口服妈富隆治疗并发症的临床效果。方法将156例药流后子宫出血超过5 d的研究对象随机分为两组:其中药流后口服妈富隆治疗者纳入观察组78例,药流后清宫者纳入对照组78例。观察两组子宫出血情况、药流后21 d的子宫内膜厚度、月经恢复时间、痛经症状、避孕效果和药物不良反应情况,并随访3个月,记录痛经、避孕失败率等情况。结果观察组与对照组子宫出血情况比较,差异无统计学意义(P>0.05);观察组子宫内膜厚度明显高于对照组,差异有统计学意义(P<0.05);观察组月经恢复、痛经症状缓解与对照组相比,差异有统计学意义(P<0.05);观察组无避孕失败,无盆腔炎表现,对照组有7例出现轻度类早孕反应,如恶心、呕吐、乏力、头晕头痛等。结论妈富隆用于药流后可以缩短子宫出血时间,调整月经周期,缓解痛经,避孕效果好,对于药物流产后妇女的生活质量的提高具有临床意义。
Objective To investigate the clinical effect of oral Marvulon treatment of complications after medical abortion. Methods 156 cases of uterine bleeding after medical abortion for more than 5 days were randomly divided into two groups: 78 cases were treated by oral Marvulodis after drug abortion, and 78 cases were treated by control group after abortion. The uterine hemorrhage, the thickness of endometrium, menstruation recovery, dysmenorrhea symptoms, contraceptive effects and adverse drug reactions were observed on the 21th day after drug abortion. The patients were followed up for 3 months and their dysmenorrhea and failure rate were recorded. Results There was no significant difference in uterine bleeding between the observation group and the control group (P> 0.05). The thickness of the endometrium in the observation group was significantly higher than that in the control group (P <0.05) There was no significant difference in the symptoms of dysmenorrhea between the control group and the control group (P <0.05). No contraceptive failure and pelvic inflammatory disease were observed in the observation group. In the control group, 7 cases had mild early pregnancy reaction such as nausea, vomiting, Dizziness, headache and so on. Conclusion Marvelon used in medical abortion can shorten the time of uterine bleeding, adjust the menstrual cycle, relieve dysmenorrhea, contraceptive effect is good, for the improvement of quality of life of women after medical abortion has clinical significance.