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c Jun氨基末端激酶 (c JunN terminalkinase ,JNK)和P3 8蛋白激酶是信号从细胞表面转导到细胞内部的重要传递者 ,与细胞的生物学功能有密切关系。JNK和P3 8活性受到多种造血因子的调节 ,JNK和P3 8通路参与了对正常及恶性造血细胞分化和凋亡的调控。
c Jun N terminal kinase (cNNK) and P3 8 protein kinase are important transducers of signal transduction from the cell surface into the cell interior, which is closely related to the biological function of cells. JNK and P3 8 activity is regulated by a variety of hematopoietic factors, and JNK and P3 8 pathways are involved in the regulation of normal and malignant hematopoietic cell differentiation and apoptosis.