目的 :观察丁咯地尔针剂用于治疗下肢动脉缺血症病人的疗效和安全性。方法 :采用多中心方法 ,同步开放给药 ,应用丁咯地尔针剂治疗 83例( 130侧肢体 )下肢动脉缺血症病人。剂量2 0 0mg·d- 1,连续静滴 3wk。结果 :治疗末期 ,患肢间隙性跛行、静息痛、皮肤麻痹症状及溃疡情况有不同程度改善 ,有效率分别为 61% ,91% ,80 %和55% ,总有效率为 80 %。用药期间未发现严重不良反应。结论 :丁咯地尔治疗下肢动脉缺血症 ,疗效显著 ,并且安全 Objective: To observe the efficacy and safety of buflomedil injection in the treatment of patients with lower extremity arterial ischemia. Methods: A total of 83 patients (130 limbs) with lower extremity arterial ischemia were treated with Buflomedil injection simultaneously. Dose 200 mg · d-1, continuous intravenous infusion 3wk. Results: At the end of treatment, the patients had lameness, resting pain, paralysis of skin and ulcer with varying degrees of improvement. The effective rates were 61%, 91%, 80% and 55%, respectively. The total effective rate was 80%. No serious adverse reactions were found during the medication. Conclusion: Buflomedil treatment of lower extremity arterial ischemia, with significant effect, and safe