Antisperm antibodies (ASA)occur in men and women and may significantly impair fertility. The identification of functionally rele-vant antigens of ASA is important for establishing causal treatment options on the one hand and may,on the other hand, enhance the de-velopment of tools for immunocon-traception. One candidate protein is addressed in an article of Wang et al. [1] published in Asian Journal of Andrology.