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长期口服鬼臼乙叉甙作为一种化疗类型,对胚细胞瘤、淋巴瘤、卡波济肉瘤和原发性脑瘤是有效的。本研究旨在评价鬼臼乙叉甙长期口服化疗的毒性反应和疗效。 复发性幕上神经胶质瘤儿童14例(男8例,女6例),年龄4～18(中位数9)岁。肿瘤组织学分级包括Daumas-Duport分级3级10例和4级星形细胞瘤4例。所有儿童以前均应用过放射治疗(中间剂量60Gy)
Long-term oral etoposide as a type of chemotherapy for blastoma, lymphoma, Kaposi’s sarcoma and primary brain tumor is effective. This study was designed to evaluate the long-term oral toxicity of etoposide and its efficacy. 14 cases of recurrent suprabasal glioma children (8 males and 6 females), aged 4 to 18 (median 9) years old. Tumor histological grade included Daumas-Duport grade 3 in 10 cases and grade 4 astrocytoma in 4 cases. All children had previously used radiation therapy (median dose 60Gy)