亚低温治疗高血压脑出血患者改善功能预后及相关因素分析

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Objective To study the effect of sub hypothermia on hypertension cerebral hemorrhage and content of serum endothelin(ET). Method 87 hypertension cerebral hemorrhage cases were divided into subhypothermia group and control group randomly,patients in subhypothermia group received subhypothermia therapy in NICU-6 hours after operation or hospitalization.We tested serum ET content with specific radioimmunoassay method 24 hours,72 hours and 3 weeks after therapy,and compared them with control group.Result ET content of two groups increased apparently after 24 hours,ET of subhypothermia group was lower than that of control group(P< 0.01);it recovered 3 weeks after therapy.Conclusion Subhypothermia techniques can apparently improve prognosis of hypertension cerebral hemorrhage patients,serum ET level may be one important index to evaluate severity of hypertension cerebral hemorrhage.
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