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恶性肿瘤治疗近10年有较大进展,但骨髓造血受抑仍然是治疗中的主要障碍。部分病人接受大剂量化疗或/和放疗后因造血受抑而感染,导致死亡。即便有部分病人因自体、胎肝输注或同种异体骨髓移植获得成功,也可能再次复发而接受再一次大剂量化疗,病人是否能经受起如此大量的化疗是目前恶性肿瘤治疗的一个重要间题。我们通过治疗前采集病人骨髓保存(以待日后复发时再用),然后用大剂量化疗,放疗预处理后,仅用胎肝移植治疗1例晚期恶性淋巴瘤患者获得成功。现报告如下:患者男性,41岁。因全身浅表淋巴结肿大1年余于1987年2月6日入院。1985年4月患者偶然发现
Malignant tumors have made great progress in the past 10 years, but inhibition of bone marrow hematopoietic remains the main obstacle in the treatment. Some patients receiving high-dose chemotherapy or / and radiation therapy due to suppression of hematopoietic infection, resulting in death. Even if some patients were successful due to autologous, fetal liver infusion or allogeneic bone marrow transplantation, they may relapse again and receive another high-dose chemotherapy. Whether the patient can withstand such a large amount of chemotherapy is an important issue in the treatment of malignant tumors question. We collected the patient’s bone marrow before treatment (to be reused later), and then treated with high-dose chemotherapy and radiotherapy. One case of advanced malignant lymphoma treated with fetal liver transplantation was successfully treated. The report is as follows: Male patient, 41 years old. Due to systemic superficial lymph nodes more than 1 year in February 6, 1987 admission. April 1985 patients found by chance