反义技术是近年发展起来的一门治疗肿瘤的新技术,已成为医学界研究的热点之一,许多反义药物已开始进入临床实验阶段,并取得了令人满意的疗效。文章主要综述了反义技术的作用机制,在白血病方面所选用的靶基因以及研究进展。 Antisense technology is a new technology developed in recent years to treat tumors. It has become one of the hot topics in the medical field. Many antisense drugs have entered clinical trials and have achieved satisfactory results. The article mainly reviewed the mechanism of antisense technology, the target genes used in leukemia and the research progress.